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CCDC113 promotes colorectal cancer tumorigenesis and metastasis via TGF-β signaling pathway

11 Sept 2024

Abstract excerpt

Colorectal cancer (CRC) is the second leading cause of cancer-related mortality worldwide. Although CRC patients' survival is improved with surgical resection and immunotherapy, metastasis and recurrence remain major problems leading to poor prognosis. Therefore, exploring pathogenesis and identifying specific biomarkers are crucial for CRC early diagnosis and targeted therapy. CCDC113, a member of CCDC families,...

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PMID: 39261464
DOI: 10.1038/s41419-024-07036-3

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