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Article

SERPINE1 as a critical CAF-associated gene promotes myCAF phenotype activation and exosome-mediated gastric cancer progression

2026-07-08

Abstract excerpt

<title>Abstract</title> <p>Purpose Cancer-associated fibroblasts (CAFs) are key components of the tumor microenvironment and are associated with poor prognosis in several cancers. SERPINE1 (serpin family E member 1; also known as plasminogen activator inhibitor-1, PAI-1) is a serine protease inhibitor that regulates extracellular matrix (ECM) remodeling and has been implicated in tumor progression. However, the...

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Literature Corpus work
997594dd-b2a2-5e40-a54d-3768a9d84b5e
DOI
10.21203/rs.3.rs-10037991/v1
Open publication

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SERPINE1 as a critical CAF-associated gene promotes myCAF phenotype activation and exosome-mediated gastric cancer progressionDOI 10.21203/rs.3.rs-10037991/v1
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