Article

A role for LGI1 in regulating pain sensitivity

2023-09-14

Abstract excerpt

Chronic pain represents a major unmet clinical need. Neuropathic pain, that is pain arising due to damage or disease of the somatosensory nervous system, represents a sizeable proportion of chronic pain cases, affecting around 8% of the general population. Neuronal hyperexcitability is a key driver of neuropathic pain. Leucine glioma inactivated 1 (LGI1), is a secreted protein known to regulate excitability within...

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Literature Corpus work: afc5bbc7-2e8e-5802-bddb-0ecff2f46e92
DOI: 10.1101/2023.09.13.557645

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