Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of efflux pump inhibition on Pseudomonas aeruginosa transcriptome and virulence.

Scientific reports - 12 Sept 2017

Rampioni Giordano, Pillai Cejoice Ramachandran, Longo Francesca, Bondì Roslen, Baldelli Valerio, Messina Marco, Imperi Francesco, Visca Paolo, Leoni Livia

Abstract excerpt

Efflux pumps of the resistance-nodulation-cell-division (RND) family increase antibiotic resistance in many bacterial pathogens, representing candidate targets for the development of antibiotic adjuvants. RND pumps have also been proposed to contribute to bacterial infection, implying that efflux pump inhibitors (EPIs) could also act as anti-virulence drugs. Nevertheless, EPIs are usually investigated only for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Dipeptides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Profiling

Share to Gene Expression Regulation, Bacterial

Share to Membrane Transport Proteins

Share to Pseudomonas aeruginosa

Share to Transcriptome

Share to Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 28900249
DOI: 10.1038/s41598-017-11892-9
PMCID: PMC5596013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of efflux pump inhibition on Pseudomonas aeruginosa transcriptome and virulence.PMID 28900249Read ↗

Evaluating the Link Between Efflux Pump Expression and Motility Phenotypes in <i>Pseudomonas aeruginosa</i> Treated with Virulence InhibitorsSemantic proximity Read ↗

Drug resistance and physiological roles of RND multidrug efflux pumps in Salmonella enterica, Escherichia coli and Pseudomonas aeruginosaSemantic proximity Read ↗

Non-interchangeable functions of efflux transporters of Pseudomonas aeruginosa in survival under infection-associated stressSemantic proximity Read ↗

RND Efflux Pump Induction: A Crucial Network Unveiling Adaptive Antibiotic Resistance Mechanisms of Gram-Negative BacteriaSemantic proximity Read ↗

The Art of War with Pseudomonas aeruginosa: Targeting Mex Efflux Pumps Directly to Strategically Enhance Antipseudomonal Drug EfficacySemantic proximity Read ↗

Antibiotic efflux mechanismsSemantic proximity Read ↗

Resistance in gram-negative bacilli: the emergence of RND efflux pumpsSemantic proximity Read ↗

The Challenge of Efflux-Mediated Antibiotic Resistance in Gram-Negative BacteriaSemantic proximity Read ↗

Functional interplay between RND efflux pumps and GacS in Pseudomonas aeruginosaSemantic proximity Read ↗

Structural and functional diversity of Resistance-Nodulation-Division (RND) efflux pump transporters with implications for antimicrobial resistanceSemantic proximity Read ↗

Update on Multidrug Resistance Efflux Pumps in Acinetobacter spp.Semantic proximity Read ↗

New alternative therapeutic strategies against Pseudomonas aeruginosa, an opportunistic multi-resistant pathogen with a myriad of virulence factors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.