Non-interchangeable functions of efflux transporters of Pseudomonas aeruginosa in survival under infection-associated stress

Abstract excerpt

ABSTRACT Pseudomonas aeruginosa is a challenging opportunistic pathogen due to its intrinsic and acquired mechanisms of antibiotic resistance. A large repertoire of efflux transporters actively expels antibiotics, toxins, and metabolites from cells and enables growth of P. aeruginosa in diverse environments. In this study, we analyzed the roles of representative efflux pumps from the...