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Regulation, structure, and activity of the Pseudomonas aeruginosa MexXY efflux system

7 Apr 2025

Abstract excerpt

ABSTRACT The current crisis in bacterial antibiotic resistance can be attributed to the overuse (or misuse) of these essential medicines in healthcare and agriculture, coupled with the slowed progression of new drug development. In the versatile, opportunistic pathogen Pseudomonas aeruginosa , the Resistance-Nodulation-Division (RND) efflux pump MexXY plays critical roles in both cell physiology and the...

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PMID: 40192483
DOI: 10.1128/aac.01825-24

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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