Article

Machine learning-based development of Gadolinium binding peptides

2025-12-16

Abstract excerpt

<h4>ABSTRACT</h4> Gadolinium-based contrast agents (GBCAs) are indispensable tools in magnetic resonance imaging (MRI), yet their clinical use is limited by non-specific tissue accumulation, low molecular specificity, and safety concerns. Protein and peptide scaffolds provide a promising alternative because they can bind metal ions with high selectivity and enable precise molecular targeting. However, identifying...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ce8ce260-86a0-5101-91e6-4fc81e44beec
DOI: 10.64898/2025.12.14.694215

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Machine learning-based development of Gadolinium binding peptidesDOI 10.64898/2025.12.14.694215Read

Computational peptide discovery with a genetic programming approachSemantic proximity Read

Protein Optimization Evolving Tool (POET) based on Genetic ProgrammingSemantic proximity Read

Machine-guided dual-objective protein engineering for deimmunization and therapeutic functionsSemantic proximity Read

Integrating Computational Design and Experimental Approaches for Next-Generation BiologicsSemantic proximity Read

Peptide design by artificial neural networks and computer-based evolutionary searchSemantic proximity Read

A Hybrid Diffusion Model for Stable, Affinity-Driven, Receptor-Aware Peptide GenerationSemantic proximity Read

De novo design of high-affinity protein binders to bioactive helical peptidesSemantic proximity Read

Multi-Objective Active Learning Overcomes Liver Tropism in LNP- Mediated mRNA Delivery to the BrainSemantic proximity Read

Aiki-GeNano: Multi-Stage Preference Optimization for Generative Design of Developable NanobodiesSemantic proximity Read

Computer-guided design of Z domain peptides with improved inhibition of VEGFSemantic proximity Read

Molecular evolution of peptide ligands with custom-tailored characteristics for targeting of glycostructures.Semantic proximity Read

In Silico Directed Evolution of Humanized Peptide Transporters via Attention-Guided Epistatic RescueSemantic proximity Read