Article

A Hybrid Diffusion Model for Stable, Affinity-Driven, Receptor-Aware Peptide Generation

2024-03-16

Abstract excerpt

<h4>ABSTRACT</h4> The convergence of biotechnology and artificial intelligence has the potential to transform drug development, especially in the field of therapeutic peptide design. Peptides are short chains of amino acids with diverse therapeutic applications that offer several advantages over small molecular drugs, such as targeted therapy and minimal side effects. However, limited oral bioavailability and enz...

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Literature Corpus work: cc6b8989-51c0-5092-869e-a96da998063c
DOI: 10.1101/2024.03.14.584934

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