Article

SIV-specific neutralizing antibody induction following selection of a PI3K drive-attenuated <i>nef</i> variant

2023-04-21

Abstract excerpt

HIV and simian immunodeficiency virus (SIV) infections are known for impaired neutralizing antibody (NAb) responses. While sequential virus-host B cell interaction appears to be basally required for NAb induction, driver molecular signatures predisposing to NAb induction still remain largely unknown. Here we describe SIV-specific NAb induction following a virus-host interplay decreasing aberrant viral drive of pho...

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Literature Corpus work: ce6889a9-30ae-5fe5-9193-97991e027b17
DOI: 10.1101/2023.04.19.537602

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