Article

Pseudouridylation of rRNA by specific snoRNA disrupts ribosomal machinery and consequently affects metabolism, longevity and neurodegeneration

2026-04-21

Abstract excerpt

In our society, ageing, longevity, and neurodegenerative diseases are major concerns of public health. Recently, in Drosophila, we have identified a new cluster of three snoRNAs, including jouvence , and showed that each of them affect longevity and neurodegeneration. As these snoRNAs are required in the epithelium of the gut, these results point-out a causal relationship between the epithelium of the gut and the...

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Literature Corpus work: 856b9143-1173-580e-ae6f-955c8e67ff47
DOI: 10.64898/2026.04.17.719250

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