Back to search

Article

A novel inducible von Willebrand Factor Cre Recombinase mouse strain to study microvascular endothelial cell-specific biological processes <i>in vivo</i>

2023-07-24

Abstract excerpt

Mouse models are invaluable to understanding fundamental mechanisms in vascular biology during development, in health and different disease states. Several constitutive or inducible models that selectively knockout or knock in genes in vascular endothelial cells exist; however, functional and phenotypic differences exist between microvascular and macrovascular endothelial cells in different organs. In order to stu...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
ce092fac-1eb1-5cfc-b671-9db6e38ce62d
DOI
10.1101/2023.07.24.550419
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A novel inducible von Willebrand Factor Cre Recombinase mouse strain to study microvascular endothelial cell-specific biological processes <i>in vivo</i>DOI 10.1101/2023.07.24.550419
Mouse models of vascular development and diseaseSemantic proximity
Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodelingSemantic proximity
Endothelial cell expression of mutant Map2k1 causes vascular malformations in mice.Semantic proximity
Increasing Endoglin Deletion in Endothelial Cells Exacerbates the Severity of Brain Arteriovenous Malformation in MouseSemantic proximity
Human von Willebrand factor gene sequences target expression to a subpopulation of endothelial cells in transgenic mice.Semantic proximity
VEGFR2 Expression Correlates with Postnatal Development of Brain Arteriovenous Malformations in a Mouse Model of Type I Hereditary Hemorrhagic TelangiectasiaSemantic proximity
Characterization of a novel EGFP reporter mouse to monitor Cre recombination as demonstrated by a Tie2 Cre mouse line.Semantic proximity
Single tyrosine mutation in VE-cadherin modulates gene lung expressions: evidence for FOXF1 mediated S1PR1 upregulation to stabilize vessels in miceSemantic proximity
Constitutive, mosaic expression of TIE2 p.L914F during mouse development causes formation of venous malformationSemantic proximity
<i>Crk/Crkl</i> regulates early angiogenesis in mouse embryos by accelerating endothelial cell maturationSemantic proximity
Smooth muscle expression of Cre recombinase and eGFP in transgenic mice.Semantic proximity
Mouse models of hereditary hemorrhagic telangiectasia: recent advances and future challengesSemantic proximity
Select a neighboring publication to make it the new centre.