Article

Single tyrosine mutation in VE-cadherin modulates gene lung expressions: evidence for FOXF1 mediated S1PR1 upregulation to stabilize vessels in mice

2023-07-31

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Rationale</h4> Phosphorylation-dephosphorylation are processes involved in the adhesion of endothelial cells (ECs) to maintain vascular integrity in adults. VE-cadherin is a target for Src-mediated Y 685 phosphorylation, identified in highly vascularized human glioblastoma where it is involved in the abnormal feature of tumor blood vessels. <h4>Objective</h4> We aimed at understanding th...

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Literature Corpus work: 45477e4b-8871-5a6a-ba17-8e4de8ef8363
DOI: 10.1101/2023.07.28.550978

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