Article

N-phosphonacetyl-L-aspartate enhances type I interferon anti-viral responses through activation of non-canonical NOD2 signaling

2022-02-08

Abstract excerpt

Type I interferon production and the expression of interferon-stimulated genes (ISGs) are key components of an innate immune response to many microbial pathogens. Dysregulation of this response can result in uncontrolled infection, inflammation, and autoimmune disease. Understanding the molecular mechanisms shaping the strength of type I interferon signaling may provide critical insights into infection control str...

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Literature Corpus work: ce05fd0d-46aa-54be-8e0d-d835954f9c8f
DOI: 10.1101/2022.02.08.479597

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