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Article

Role of nucleotide-binding oligomerization domain 1 (NOD1) and its variants in human cytomegalovirus control in vitro and in vivo.

Proceedings of the National Academy of Sciences of the United States of America - 29 Nov 2016

Fan Yi-Hsin, Roy Sujayita, Mukhopadhyay Rupkatha, Kapoor Arun, Duggal Priya, Wojcik Genevieve L, Pass Robert F, Arav-Boger Ravit

Abstract excerpt

Induction of nucleotide-binding oligomerization domain 2 (NOD2) and downstream receptor-interacting serine/threonine-protein kinase 2 (RIPK2) by human cytomegalovirus (HCMV) is known to up-regulate antiviral responses and suppress virus replication. We investigated the role of nucleotide-binding oligomerization domain 1 (NOD1), which also signals through RIPK2, in HCMV control. NOD1 activation by Tri-DAP (NOD1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27856764
DOI: 10.1073/pnas.1611711113
PMCID: PMC5137695

Genes

NOD1
RIPK2
DAP
NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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