Article

Looking Beyond the Cytogenetics in Haematological Malignancies- Decoding the Role of Tandem Repeats in DNA Repair Genes

2022-05-06

Abstract excerpt

<title>Abstract</title> <p><bold>Background -</bold> In cancer research, one of the most significant findings was to characterize the DNA repair deficiency as carcinogenic. Amongst the various repair mechanisms, mismatch repair (MMR) and direct reversal of DNA damage (DRD) systems are designated as multilevel safeguards in the human genome. Defects in these elevate the rate of mutations and results in dire conseq...

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Literature Corpus work: cd110712-25e9-5007-b325-b49c233143e8
DOI: 10.21203/rs.3.rs-1592530/v1

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