Article

Regulation of Epithelial HIF by Probiotic <i>Escherichia coli</i>

2025-05-15

Abstract excerpt

The gastrointestinal tract is home to trillions of microorganisms that interact with their host in profound ways, including regulation of immune, endocrine, and neurological functions. One mechanism by which these microbes interact with their eukaryotic host is through the generation of short-chain fatty acids (SCFAs), which are metabolized by the intestinal epithelium creating a state of “physiologic hypoxia”. Th...

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Literature Corpus work: ccdbb1d2-dee4-5d24-9a88-d8a7c3adde05
DOI: 10.1101/2025.05.14.654147

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