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Conditional deletion of HIF-1α provides new insight regarding the murine response to gastrointestinal infection with <i>Salmonella</i> Typhimurium

2021-01-16

Abstract excerpt

The hypoxia-inducible transcription factor 1 (HIF-1) has been shown to ameliorate different bacterial infections through enhancement of microbial killing. While the impact of HIF-1 on inflammatory diseases of the gut has been studied intensively, its function in bacterial infections of the intestine remains largely elusive. With the help of a publicly available gene expression data set, we could infer significant...

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Literature Corpus work
b9018fb5-5b79-53c3-9eac-371f05c4825a
DOI
10.1101/2021.01.16.426940
Open publication

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Conditional deletion of HIF-1α provides new insight regarding the murine response to gastrointestinal infection with <i>Salmonella</i> TyphimuriumDOI 10.1101/2021.01.16.426940
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