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Article

Selective induction of integrin βi by hypoxia‐inducible factor: implications for wound healing

22 Dec 2008

Abstract excerpt

Because of localized vascular damage and increased tissue oxygen demand, wound healing occurs in a relatively hypoxic microenvironment. These features are particularly relevant to wound healing and fibrosis in chronic inflammatory conditions, such as Crohn's disease and ulcerative colitis. In these studies, we sought to identify the contribution of hypoxia to mechanisms of wound repair in a model of the...

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PMID: 19103643
DOI: 10.1096/fj.08-125344

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