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The presence of a G-quadruplex prone sequence upstream of a minimal promoter increases transcriptional activity in the yeast <i>S. cerevisiae</i>

2023-06-26

Abstract excerpt

Non-canonical secondary structures in DNA are increasingly being revealed as critical players in DNA metabolism, including modulating the accessibility and activity of promoters. These structures comprise the so-called G-quadruplexes (G4s) that are formed from sequences rich in guanine bases. Using a well-defined transcriptional reporter system, we sought to systematically investigate the impact of the presence of...

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Literature Corpus work
ccda04f9-7ac1-5d0d-b7bc-811b701a00a1
DOI
10.1101/2023.06.23.546269
Open publication

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The presence of a G-quadruplex prone sequence upstream of a minimal promoter increases transcriptional activity in the yeast <i>S. cerevisiae</i>DOI 10.1101/2023.06.23.546269
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