Article
Genomic distribution and functional analyses of potential G-quadruplex-forming sequences in Saccharomyces cerevisiae.
Nucleic acids research - 1 Jan 2008
Hershman Steve G, Chen Qijun, Lee Julia Y, Kozak Marina L, Yue Peng, Wang Li-San, Johnson F Brad
Abstract excerpt
Although well studied in vitro, the in vivo functions of G-quadruplexes (G4-DNA and G4-RNA) are only beginning to be defined. Recent studies have demonstrated enrichment for sequences with intramolecular G-quadruplex forming potential (QFP) in transcriptional promoters of humans, chickens and bacteria. Here we survey the yeast genome for QFP sequences and similarly find strong enrichment for these sequences in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
