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Article

The DNA methylation landscape of five pediatric-tumor types

2021-08-03

Abstract excerpt

Fewer DNA mutations have been identified in pediatric tumors than adult tumors, suggesting that alternative tumorigenic mechanisms, including aberrant DNA methylation, may play a prominent role in pediatric tumors. Methylation is an epigenetic process of regulating gene expression in which methyl groups are attached to DNA molecules, often in promoter regions. In Wilms tumors and acute myeloid leukemias, increased...

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Literature Corpus work
cbfa3f20-1343-5ef6-8e36-01ef2d2b0905
DOI
10.1101/2021.08.02.454814
Open publication

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The DNA methylation landscape of five pediatric-tumor typesDOI 10.1101/2021.08.02.454814
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