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Classification of pediatric soft and bone sarcomas using DNA methylation-based profiling

20 Nov 2024

Abstract excerpt

Pediatric sarcomas present heterogeneous morphology, genetics and clinical behavior posing a challenge for an accurate diagnosis. DNA methylation is an epigenetic modification that coordinates chromatin structure and regulates gene expression, determining cell type and function. DNA methylation-based tumor profiling classifier for sarcomas (known as sarcoma classifier) from the German Cancer Research Center...

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Share to Epigenetics and DNA Methylation
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PMID: 39567898
DOI: 10.1186/s12885-024-13159-9

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