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Targeting DNA Methylation Machinery in Pediatric Solid Tumors

18 Jul 2024

Abstract excerpt

DNA methylation is a key epigenetic regulatory mechanism that plays a critical role in a variety of cellular processes, including the regulation of cell fate during development, maintenance of cell identity, and genome stability. DNA methylation is tightly regulated by enzymatic reactions and its deregulation plays an important role in the development of cancer. Specific DNA methylation alterations have been...

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PMID: 39056791
DOI: 10.3390/cells13141209

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