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Understanding the epigenetic landscape and cellular architecture of childhood brain tumors.

Neurochemistry international - 1 Mar 2021

Alencastro Veiga Cruzeiro Gustavo, Rota Christopher, Hack Olivia A, Segal Rosalind, Filbin Mariella G

Abstract excerpt

Pediatric brain tumors are the leading cancer-related cause of death in children and adolescents in the United States, affecting on average 1 in 2000 children per year. Recent advances in cancer genomics have led to profound discoveries about the underlying molecular biology and ontogeny of these tumors. In particular, these studies have revealed epigenetic dysregulation to be one of the main hallmarks of...

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Age Factors
Brain Neoplasms
Child
DNA Methylation
Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33333210
DOI: 10.1016/j.neuint.2020.104940

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