Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic Changes in Pediatric Solid Tumors: Promising New Targets

14 May 2012

Abstract excerpt

Cancer is being reinterpreted in the light of recent discoveries related to the histone code and the dynamic nature of epigenetic regulation and control of gene programs during development, as well as insights gained from whole cancer genome sequencing. Somatic mutations in or deregulated expression of genes that encode chromatin-modifying enzymes are being identified with high frequency. Nowhere is this more...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin Remodeling and Cancer
Share to Epigenetics and DNA Methylation
Share to Neuroblastoma Research and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22589485
DOI: 10.1158/1078-0432.ccr-11-1921

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic Changes in Pediatric Solid Tumors: Promising New TargetsPMID 22589485Read ↗

The growing role of epigenetics in childhood cancersSemantic proximity Read ↗

Understanding the epigenetic landscape and cellular architecture of childhood brain tumors.Semantic proximity Read ↗

Oncohistones: drivers of pediatric cancers.Semantic proximity Read ↗

The genomic landscape of pediatric cancers: Implications for diagnosis and treatmentSemantic proximity Read ↗

Molecular Markers of Pediatric Solid Tumors—Diagnosis, Optimizing Treatments, and Determining Susceptibility: Current State and Future DirectionsSemantic proximity Read ↗

Mutations in chromatin machinery and pediatric high-grade glioma.Semantic proximity Read ↗

Epigenetic reprogramming in pediatric gliomas: from molecular mechanisms to therapeutic implications.Semantic proximity Read ↗

Targeting DNA Methylation Machinery in Pediatric Solid TumorsSemantic proximity Read ↗

Epigenetic dysregulation: a novel pathway of oncogenesis in pediatric brain tumorsSemantic proximity Read ↗

The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes.Semantic proximity Read ↗

Developmental origins shape the paediatric cancer genome.Semantic proximity Read ↗

Epigenetic Modifications in Pediatric Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.