Article

CLASS: Accurate and Efficient Splice Variant Annotation from RNA-seq Reads

2014-11-20

Abstract excerpt

<h4>ABSTRACT</h4> Next generation sequencing of cellular RNA is making it possible to characterize genes and alternative splicing in unprecedented detail. However, designing bioinformatics tools to capture splicing variation accurately has proven difficult. Current programs find major isoforms of a gene but miss finer splicing variations, or are sensitive but highly imprecise. We present CLASS, a novel open sourc...

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Literature Corpus work: 82e63b5c-efaa-5b4f-8210-27ab185e8a2f
DOI: 10.1101/011718

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