Article

Improved Transcriptome Assembly Using a Hybrid of Long and Short Reads with StringTie

2021-12-10

Abstract excerpt

Short-read RNA sequencing and long-read RNA sequencing each have their strengths and weaknesses for transcriptome assembly. While short reads are highly accurate, they are unable to span multiple exons. Long-read technology can capture full-length transcripts, but its high error rate often leads to mis-identified splice sites, and its low throughput makes quantification difficult. Here we present a new release of...

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Literature Corpus work: 04fd165a-a781-57f2-893b-fdc5acaca511
DOI: 10.1101/2021.12.08.471868

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