Article
Analysis of Bcl6 in a genetically tractable human B cell line
2010-01-01
Abstract excerpt
B cell lymphoma 6 (Bcl6) is a proto-oncogene functioning as a transcriptional repressor at the germinal centre (GC) stage of B cell development, regulating proliferation, differentiation and survival. Bcl6 is commonly dysregulated in GCderived lymphomas and hence a promising therapeutic target. Although a number of agents targeting Bcl6 are being developed, there is currently no good model available for functional...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- cb5a4134-e300-51d3-880b-8392aec6c5c8
- DOI
- 10.25560/6047