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Article

BCL6 as a therapeutic target for lymphoma.

Expert opinion on therapeutic targets - 1 Feb 2018

Leeman-Neill Rebecca J, Bhagat Govind

Abstract excerpt

INTRODUCTION: B cell lymphoma 6 (BCL6) is a transcriptional repressor critical for the development and maintenance of germinal centers (GCs), which are required for generation of an effective humoral immune response. Genomic aberrations of BCL6, including mutations and translocations that occur during the GC reaction, as well as alterations of genes that regulate BCL6 expression, lead to sustained activity of...

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Topics

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Share to Antineoplastic Agents
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Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphoma

Share to Molecular Targeted Therapy

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Share to Proto-Oncogene Proteins c-bcl-6

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Source

Identifiers

PMID: 29262721
DOI: 10.1080/14728222.2018.1420782

Genes

BCL6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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