Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

B Cell Lymphoma 6 (BCL6): A Conserved Regulator of Immunity and Beyond

11 Oct 2024

Abstract excerpt

B cell lymphoma 6 (BCL6) is a conserved multi-domain protein that functions principally as a transcriptional repressor. This protein regulates many pivotal aspects of immune cell development and function. BCL6 is critical for germinal center (GC) formation and the development of high-affinity antibodies, with key roles in the generation and function of GC B cells, follicular helper T (Tfh) cells, follicular...

Topics

Join the communities discussing this publication.

Chronic Lymphocytic Leukemia Research
Immune Cell Function and Interaction
Lymphoma Diagnosis and Treatment

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39456751
DOI: 10.3390/ijms252010968

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

B Cell Lymphoma 6 (BCL6): A Conserved Regulator of Immunity and BeyondPMID 39456751Read ↗

Roles of BCL6 in normal and transformed germinal center B cellsSemantic proximity Read ↗

B-cell Lymphoma 6 (BCL6): From Master Regulator of Humoral Immunity to Oncogenic Driver in Pediatric CancersSemantic proximity Read ↗

Mechanisms of action of BCL6 during germinal center B cell developmentSemantic proximity Read ↗

BCL6 as a therapeutic target for lymphoma.Semantic proximity Read ↗

The proto-oncogene BCL-6 in normal and malignant B cell development.Semantic proximity Read ↗

Bcl6-Mediated Transcriptional Regulation of Follicular Helper T cells (TFH)Semantic proximity Read ↗

Germinal center‐derived lymphomas: The darkest side of humoral immunitySemantic proximity Read ↗

Molecular Pathogenesis of Non-Hodgkin's Lymphoma: the Role of Bcl-6Semantic proximity Read ↗

Bcl6: where too much complexity is barely enough.Semantic proximity Read ↗

BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanismsSemantic proximity Read ↗

Mutational, immune microenvironment, and clinicopathological profiles of diffuse large B-cell lymphoma and follicular lymphoma with BCL6 rearrangement.Semantic proximity Read ↗

A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.