Article

Novel function of <i>Hox13</i> in regulating outgrowth of the newt hindlimb bud through interaction with <i>Fgf10</i> and <i>Tbx4</i>

2024-11-14

Abstract excerpt

5’ Hox genes regulate pattern formation along the axes of the limb. Previously, we showed that Hoxa13/Hoxd13 double mutant newts lacked all digits of the forelimbs during development and regeneration, showing that newt Hox13 is necessary for digit formation in development and regeneration. In addition, we found another unique phenotype. A part of the Hox13 crispant newts showed hindlimb defects, in which whole...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cb246999-0de1-512a-9b3b-6ab676f1cadf
DOI: 10.1101/2024.11.12.623306

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Novel function of <i>Hox13</i> in regulating outgrowth of the newt hindlimb bud through interaction with <i>Fgf10</i> and <i>Tbx4</i>DOI 10.1101/2024.11.12.623306Read

Hoxd13/Bmp2-mediated mechanism involved in zebrafish finfold design.Semantic proximity Read

Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs.Semantic proximity Read

Tail gut endoderm and gut/genitourinary/tail development: a new tissue-specific role for Hoxa13.Semantic proximity Read

Hoxa-13 and Hoxd-13 play a crucial role in the patterning of the limb autopod.Semantic proximity Read

Altered Hox expression and increased cell death distinguish Hypodactyly from Hoxa13 null mice.Semantic proximity Read

SPECIFIC ECTODERMAL ENHANCERS CONTROL THE EXPRESSION OF <i>Hoxc</i> GENES IN DEVELOPING MAMMALIAN INTEGUMENTSSemantic proximity Read

Fndc3a (Fibronectin Domain Containing Protein 3A) influences median fin fold development and caudal fin regeneration in zebrafish by ECM alterationSemantic proximity Read

Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation.Semantic proximity Read

Spatio‐temporal expression of <i>HOX</i> genes in human hindgut developmentSemantic proximity Read

Limbs: a model for pattern formation within the vertebrate body plan.Semantic proximity Read

Medaka unextended-fin mutants suggest a role for Hoxb8a in cell migration and osteoblast differentiation during appendage formation.Semantic proximity Read

Development of a ZRS Reporter System for the Newt (<em>Cynops pyrrhogaster</em>) during Terrestrial Limb RegenerationSemantic proximity Read