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Article

Medaka unextended-fin mutants suggest a role for Hoxb8a in cell migration and osteoblast differentiation during appendage formation.

Developmental biology - 15 May 2006

Sakaguchi Sae, Nakatani Yuki, Takamatsu Naofumi, Hori Hiroshi, Kawakami Atsushi, Inohaya Keiji, Kudo Akira

Abstract excerpt

Hoxb8 has been suggestively implicated in the formation of the zone of polarizing activity (ZPA) in the limb bud. However, as hoxb8-/- mice did not show any defects in their limb development, the role of Hoxb8 during limb development has not been fully elucidated. Here, we report the identification of the medaka hoxb8a mutant, unextended-fin (ufi), in which all the fin tissues were malformed. Since the abnormal...

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PMID: 16546159
DOI: 10.1016/j.ydbio.2006.02.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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