Article
Tail gut endoderm and gut/genitourinary/tail development: a new tissue-specific role for Hoxa13.
Development (Cambridge, England) - 1 Feb 2002
de Santa Barbara Pascal, Roberts Drucilla J
Abstract excerpt
Hoxa13 is expressed early in the caudal mesoderm and endoderm of the developing hindgut. The tissue-specific roles of Hoxa13 function have not been described. Hand-foot-genital syndrome, a rare dominantly inherited human malformation syndrome characterized by distal extremity and genitourinary anomalies, is caused by mutations in the HOXA13 gene. We show evidence that one specific HOXA13 mutation likely acts as a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
