Article

Neural precursor cells rescue symptoms of Rett syndrome by activation of the Interferon γ pathway

2024-01-08

Abstract excerpt

The beneficial effects of Neural Precursor Cell (NPC) transplantation in several neurological disorders are well established and they are generally mediated by the secretion of immunomodulatory and neurotrophic molecules. We therefore investigated whether Rett syndrome (RTT), that represents the first cause of severe intellectual disability in girls, might benefit from an NPC-based therapy. Using in vitro co-cult...

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Literature Corpus work: cb205a9e-2033-56f9-924d-41651e6c7cdd
DOI: 10.1101/2024.01.07.574507

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