Article

Unveiling Cell Wall Structure and Echinocandin Response in <i>Candida auris</i> and <i>Candida albicans</i> via Solid-State NMR

2024-12-03

Abstract excerpt

<h4>ABSTRACT</h4> Invasive candidiasis affects 1.6 million people annually, implicating high mortality and morbidity in immunocompromised and hospitalized patients. Echinocandins, inhibitors of β-1,3-glucan synthesis, are used as a first-line treatment; however, their efficacy is increasingly compromised by resistance and tolerance. To understand how echinocandins remodel Candida cell wall structures, thereby re...

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Literature Corpus work: cb095fcc-aebb-5d21-8cd5-07e2626c6425
DOI: 10.1101/2024.12.02.626508

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