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Solid-state NMR spectroscopy identifies three classes of lipids in <i>C. neoformans</i> melanized cell walls and whole fungal cells

2020-07-13

Abstract excerpt

A primary virulence-associated trait of the opportunistic fungal pathogen Cryptococcus neoformans is the production of melanin pigments that are deposited into the cell wall and interfere with the host immune response. Previously, our solid-state NMR studies of isolated melanized cell walls (melanin ‘ghosts’) revealed that the pigments are strongly associated with lipids, but their identities, origins, and potent...

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Literature Corpus work
e21dca82-8b0a-5c87-9edf-9041d927f1db
DOI
10.1101/2020.07.13.200741
Open publication

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Solid-state NMR spectroscopy identifies three classes of lipids in <i>C. neoformans</i> melanized cell walls and whole fungal cellsDOI 10.1101/2020.07.13.200741
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