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<i>FKS1/2</i> -variant independent mechanisms underlying the emergence of resistance in echinocandin-refractory <i>Candida auris</i> infections

2026-01-18

Abstract excerpt

The emerging fungus Candida auris is a drug resistant global public health threat and WHO critical priority pathogen. Recommended first-line invasive candidiasis treatment is echinocandin monotherapy, but C. auris can develop on-treatment resistance via FKS1/2 gene mutations and additional, previously unexplained mechanisms. To better understand echinocandin failure in C. auris , we sequenced the genomes of ec...

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Literature Corpus work
af98eb87-f8ab-599b-8fb3-5088d87247e7
DOI
10.64898/2026.01.17.700071
Open publication

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