Article
Mutation, biofilm formation, and cell wall remodeling contribute to echinocandin resistance of Candidozyma auris.
Future microbiology - 1 Mar 2026
Yang Xi, Ge Anni, Zhou Hao, Hu Cai, Yang Xinni, Song Zhangyong, Xin Caiyan
Abstract excerpt
AIM: This study systematically elucidates the mechanisms of echinocandin resistance in Candidozyma auris (C. auris), providing insights into potential therapeutic strategies. METHODS: Echinocandin susceptibility of clinical bloodstream C. auris isolates was determined using E-test, and resistance-associated mutations were identified by Sanger sequencing. Biofilm formation under antifungal stress was assessed by...
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