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Article

A molecular vision of fungal cell wall organization by functional genomics and solid-state NMR.

Nature communications - 3 Nov 2021

Chakraborty Arnab, Fernando Liyanage D, Fang Wenxia, Dickwella Widanage Malitha C, Wei Pingzhen, Jin Cheng, Fontaine Thierry, Latgé Jean-Paul, Wang Tuo

Abstract excerpt

Vast efforts have been devoted to the development of antifungal drugs targeting the cell wall, but the supramolecular architecture of this carbohydrate-rich composite remains insufficiently understood. Here we compare the cell wall structure of a fungal pathogen Aspergillus fumigatus and four mutants depleted of major structural polysaccharides. High-resolution solid-state NMR spectroscopy of intact cells reveals...

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Identifiers

PMID: 34732740
DOI: 10.1038/s41467-021-26749-z
PMCID: PMC8566572

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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