Article
Epigenetic regulation of retrotransposons within the nucleolus of Drosophila.
Molecular and cellular biology - 1 Oct 2008
Eickbush Danna G, Ye Junqiang, Zhang Xian, Burke William D, Eickbush Thomas H
Abstract excerpt
R2 retrotransposable elements exclusively insert into a conserved region of the tandemly organized 28S rRNA genes. Despite inactivating a subset of these genes, R2 elements have persisted in the ribosomal DNA (rDNA) loci of insects for hundreds of millions of years. Controlling R2 proliferation was addressed in this study using lines of Drosophila simulans previously shown to have either active or inactive R2...
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