Article

Flow cytometric isolation of drug-like conformational antibodies specific for amyloid fibrils

2023-07-04

Abstract excerpt

<h4>ABSTRACT</h4> Antibodies that recognize specific protein conformational states are broadly important for research, diagnostic and therapeutic applications, yet they are difficult to generate in a predictable and systematic manner using either immunization or in vitro antibody display methods. This problem is particularly severe for conformational antibodies that recognize insoluble antigens such as amyloid f...

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Literature Corpus work: ca9346a1-05d8-5ad3-aa31-1e9765158e39
DOI: 10.1101/2023.07.04.547698

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