Article

Microfluidics-enabled fluorescence-activated cell sorting of single pathogen-specific antibody secreting cells for the rapid discovery of monoclonal antibodies

2023-01-12

Abstract excerpt

Monoclonal antibodies are increasingly used to prevent and treat viral infections, playing a pivotal role in pandemic response efforts. Antibody secreting cells (ASCs, plasma cells and plasmablasts) are an excellent source of high-affinity antibodies with therapeutic potential. Current methodologies to study antigen-specific ASCs either have low throughput, require expensive and labour-intensive screening or are t...

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Literature Corpus work: 7ee7dde0-2f79-5b5f-b6d0-e35d29fbcdb2
DOI: 10.1101/2023.01.10.523494

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