Article

CEN-tools: An integrative platform to identify the ‘contexts’ of essential genes

2020-05-11

Abstract excerpt

I. <h4>ABSTRACT</h4> An emerging theme from large-scale genetic screens that identify genes essential for fitness of a cell, is that essentiality of a given gene is highly context-specific and depends on a number of genetic and environmental factors. Identification of such contexts could be the key to defining the function of the gene and also to develop novel therapeutic interventions. Here we present CEN-tools...

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Literature Corpus work: 401ee561-3c0c-5ac2-a309-ff5f715315b5
DOI: 10.1101/2020.05.10.087668

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