Article

Transcriptomic analysis of native versus cultured human and mouse dorsal root ganglia focused on pharmacological targets

2019-09-12

Abstract excerpt

Dorsal root ganglion (DRG) neurons detect sensory inputs and are crucial for pain processing. They are often studied in vitro as dissociated cell cultures with the assumption that this reasonably represents in vivo conditions. However, to our knowledge, no study has ever directly compared genome-wide transcriptomes of DRG tissue in vivo versus in vitro , or between different labs and culturing protocols. We ex...

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Literature Corpus work: 4a93aced-75c7-5eb8-a5a4-c82b6e634b04
DOI: 10.1101/766865

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