Article

A dual-function variant on chromosome 17 regulates circRNA expression and splicing in multiple sclerosis

2026-03-20

Abstract excerpt

Multiple sclerosis (MS) is a chronic autoimmune demyelinating disease of the central nervous system with a complex etiology. Recent genomic studies highlight the contribution of expression quantitative trait loci (eQTLs) in modulating gene expression and disease susceptibility. Given the emerging role of circular RNAs (circRNAs) in MS, we hypothesized that genetic variants may regulate circRNA expression through c...

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Literature Corpus work: ca480a25-6826-56d9-8665-4ffe1a8ae0e6
DOI: 10.64898/2026.03.18.712599

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