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Article

Identification of the genetic mechanism that associates L3MBTL3 to multiple sclerosis.

Human molecular genetics - 7 Jul 2022

Alcina Antonio, Fedetz Maria, Vidal-Cobo Isabel, Andrés-León Eduardo, García-Sánchez Maria-Isabel, Barroso-Del-Jesus Alicia, Eichau Sara, Gil-Varea Elia, Luisa-Maria Villar, Saiz Albert, Leyva Laura, Vandenbroeck Koen, Otaegui David, Izquierdo Guillermo, Comabella Manuel, Urcelay Elena, Matesanz Fuencisla

Abstract excerpt

Multiple sclerosis (MS) is a complex and demyelinating disease of the central nervous system. One of the challenges of the post-genome-wide association studies (GWAS) era is to understand the molecular basis of statistical associations to reveal gene networks and potential therapeutic targets. The L3MBTL3 locus has been associated with MS risk by GWAS. To identify the causal variant of the locus, we performed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35088080
DOI: 10.1093/hmg/ddac009
PMCID: PMC9262392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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