Article
Common variation in the MOG gene influences transcript splicing in humans.
Journal of neuroimmunology - 15 Dec 2010
Jensen Cathy J, Stankovich Jim, Butzkueven Helmut, Oldfield Brian J, Rubio Justin P
Abstract excerpt
Multiple sclerosis (MS) is a complex autoimmune disease characterised by demyelinating lesions in the central nervous system (CNS) and myelin oligodendrocyte glycoprotein (MOG), a CNS-restricted protein expressed on the outer cell membrane of oligodendrocytes, has been linked with disease pathogenesis. We have investigated whether expression of MOG in post-mortem human brain tissue is associated with genetic...
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