Article

The length distribution and multiple specificity of naturally presented HLA-I ligands

2018-05-31

Abstract excerpt

HLA-I molecules bind short peptides and present them for recognition by CD8+ T cells. The length of HLA-I ligands typically ranges from 8 to 12 amino acids, but variability is observed across different HLA-I alleles. Here we collected recent in-depth HLA peptidomics data, including 12 newly generated HLA peptidomes (31,896 unique peptides) from human meningioma samples, to analyze the peptide length distribution a...

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Literature Corpus work: ca3f06c1-8477-56ff-a7ec-fa3b5dc823e5
DOI: 10.1101/335661

Open publication

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