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Identification of presented SARS-CoV-2 HLA class I and HLA class II peptides using HLA peptidomics

1 Jun 2021

Abstract excerpt

The human leukocyte antigen (HLA)-bound viral antigens serve as an immunological signature that can be selectively recognized by T cells. As viruses evolve by acquiring mutations, it is essential to identify a range of presented viral antigens. Using HLA peptidomics, we are able to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-derived peptides presented by highly prevalent HLA class I...

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PMID: 34166618
DOI: 10.1016/j.celrep.2021.109305

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