Article

Unsupervised mining of HLA-I peptidomes reveals new binding motifs and substantial false positives in community database

2021-09-22

Abstract excerpt

Modern vaccine designs and studies of human leukocyte antigen (HLA)-mediated immune responses rely heavily on the knowledge of HLA allele-specific binding motifs and computational prediction of HLA-peptide binding affinity. Breakthroughs in HLA peptidomics have considerably expanded the databases of natural HLA ligands and enabled detailed characterizations of HLA-peptide binding specificity. However, cautions mus...

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Literature Corpus work: 98d81d08-fada-5704-9b3b-ae18c652d54b
DOI: 10.1101/2021.09.19.460988

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